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Seminars
Contact :
Hèléne Berthoumieux
Tel : +33 (0) 1 40 79 xx xx
Paddy Royall
Tel : +33 (0) 1 40 79 xx xx
Gulliver seminars take place on Mondays at 11:30 AM in the F304 room, and typically last one hour including questions. The seminars are in English, and the scientific topics are mainly those studied in the laboratory.
Séminaire GULLIVER
Phase-Separated Droplets Swim to Their Dissolution
Cells control vital bio-chemical processes by creating compartments with distinct compositions. In addition to the well-known membrane-bound organelles, such as the nucleus or chloroplasts,
dynamic membraneless compartments formed through liquid-liquid phase separation have merged as important cellular constituents over the last decades. These biomolecular ondensates are liquid- like, their absence of membrane allow easy chemical exchanges with their surroundings, they can coalesce, exert capillary forces and dissolve or condense easily. While their formation and liquid-like properties are well established, much less is known on the effect of biochemical activity on them. In this talk, I will present our artificial chemically active biomolecular condensates based on Bovine Serum Albumin (BSA) rich droplets seeded with enzymes. I will show that the enzymatic activity can generate concentrations gradients that drives Marangoni swimming. Yet, only specific molecules trigger this Marangoni response in our surfactant free system. I will show that the surface tension variations emerge from local perturbations of the thermodynamic phase equilibrium and can be easily summarized as : phase-separated droplets swim to their dissolution.
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Seminars (2)
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Gulliver Seminar : Haim Diamant (Tel Aviv University)
Lundi 29 avril de 11h30 à 12h30 - C162
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Gulliver seminar : Matthew Turner
Lundi 13 mai de 11h30 à 12h30 - C162
The audience is often heterogeneous - because of the wide range of scientific topics covered in the lab - so planning a talk for a broader audience would be preferred. The seminar is in English, and speakers are thus invited to prepare their slides in English.
The seminar starts at 11:30 AM. The speaker is asked to arrive in the lab at least 15 minutes in advance to set up their computer. The talks last typically 45 minutes, and are followed by a discussion time.